When to Order Metagenomic Next-Generation Sequencing (mNGS)?
mNGS is a novel, "pathogen-agnostic" diagnostic approach that enables the detection of a wide range of infectious agents by sequencing all genetic material in a sample.
A new study highlights, among other findings, the types of clinical samples where this approach results in the highest diagnostic yield:
Major determinants of pathogen detection by mNGS are immune status and initial level of suspicion of infection.
Red square added by me. PID = Primary immunodeficiency. SID = Secondary immunodeficiency.
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